Gestación, neonatos




1
. Sugiero revisar el siguiente posteo:

Partos y puerperios en tiempos del coronavirus.https://elcoronavirusdewuhan.blogspot.com/2020/03/partos-y-puerperios-en-tiempos-del.html


2
. Compilación de textos:

Un análisis de 38 mujeres embarazadas con COVID-19, sus recién nacidos y la transmisión materno-fetal de SARS-CoV-2: infecciones por coronavirus maternos y resultados del embarazo.
An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes.
Arch Pathol Lab Med. 2020 Mar 17. doi: 10.5858/arpa.2020-0901-SA. [Epub ahead of print]

Abstract
The emergence of a novel coronavirus, termed SARS-CoV-2, and the potentially life-threating respiratory disease that it can produce, COVID-19, has rapidly spread across the globe creating a massive public health problem. Previous epidemics of many emerging viral infections have typically resulted in poor obstetrical outcomes including maternal morbidity and mortality, maternal-fetal transmission of the virus, and perinatal infections and death. This communication reviews the effects of two previous coronavirus infections - severe acute respiratory syndrome (SARS) caused by SARS-CoV and Middle East respiratory syndrome (MERS) caused by MERS-CoV - on pregnancy outcomes. In addition, it analyzes literature describing 38 pregnant women with COVID-19 and their newborns in China to assess the effects of SARS-CoV-2 on the mothers and infants including clinical, laboratory and virologic data, and the transmissibility of the virus from mother to fetus. This analysis reveals that unlike coronavirus infections of pregnant women caused by SARS and MERS, in these 38 pregnant women COVID-19 did not lead to maternal deaths. Importantly, and similar to pregnancies with SARS and MERS, there were no confirmed cases of intrauterine transmission of SARS-CoV-2 from mothers with COVID-19 to their fetuses. All neonatal specimens tested, including in some cases placentas, were negative by rt-PCR for SARS-CoV-2. At this point in the global pandemic of COVID-19 infection there is no evidence that SARS-CoV-2 undergoes intrauterine or transplacental transmission from infected pregnant women to their fetuses. Analysis of additional cases is necessary to determine if this remains true.

Posibles resultados maternos e infantiles de coronavirus (Wuhan) 2019-nCoV que infectan a mujeres embarazadas: lecciones de SARS, MERS y otras infecciones por coronavirus humanos.
Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections.
Viruses. 2020 Feb 10;12(2). pii: E194. doi: 10.3390/v12020194.

Abstract
In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of China. Further investigation revealed these cases to result from infection with a newly identified coronavirus, termed the 2019-nCoV. The infection moved rapidly through China, spread to Thailand and Japan, extended into adjacent countries through infected persons travelling by air, eventually reaching multiple countries and continents. Similar to such other coronaviruses as those causing the Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS), the new coronavirus was reported to spread via natural aerosols from human-to-human. In the early stages of this epidemic the case fatality rate is estimated to be approximately 2%, with the majority of deaths occurring in special populations. Unfortunately, there is limited experience with coronavirus infections during pregnancy, and it now appears certain that pregnant women have become infected during the present 2019-nCoV epidemic. In order to assess the potential of the Wuhan 2019-nCoV to cause maternal, fetal and neonatal morbidity and other poor obstetrical outcomes, this communication reviews the published data addressing the epidemiological and clinical effects of SARS, MERS, and other coronavirus infections on pregnant women and their infants. Recommendations are also made for the consideration of pregnant women in the design, clinical trials, and implementation of future 2019-nCoV vaccines.
KEYWORDS: 2019-nCoV; China; MERS-CoV; Middle East respiratory syndrome; SARS-CoV; Wuhan coronavirus; Wuhan coronavirus outbreak; coronavirus; emerging infection; epidemic; maternal death; maternal morbidity; maternal mortality; pneumonia; pregnancy; pregnancy complications; severe acute respiratory syndrome

Posible transmisión vertical de SARS-CoV-2 de una madre infectada a su recién nacido
Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn
JAMA. Published online March 26, 2020. doi:10.1001/jama.2020.4621
Infección neonatal de inicio temprano con SARS-CoV-2 en 33 recién nacidos de madres con COVID-19 en Wuhan, China
Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China
JAMA Pediatr. Published online March 26, 2020. doi:10.1001/jamapediatrics.2020.0878
Nueva enfermedad del virus corona (COVID-19) en el embarazo: ¿Qué recomendaciones clínicas seguir?
Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow?
Acta Obstet Gynecol Scand. 2020 Apr;99(4):439-442. doi: 10.1111/aogs.13836. Epub 2020 Mar 5.

Enfermedad por coronavirus 2019 (COVID-19) y embarazo: lo que los obstetras deben saber.
Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know.
Am J Obstet Gynecol. 2020 Feb 24. pii: S0002-9378(20)30197-6. doi: 10.1016/j.ajog.2020.02.017. [Epub ahead of print]

Abstract
Coronavirus Disease 2019 (COVID-19) is an emerging disease with a rapid increase in cases and deaths since its first identification in Wuhan, China, in December 2019. Limited data are available about COVID-19 during pregnancy; however, information on illnesses associated with other highly pathogenic coronaviruses (i.e., severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS)) might provide insights into COVID-19's effects during pregnancy.

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